Biological understanding of top genetic alterations across tumor types
Novel anti-cancer drug targeting
Reactivation of mutant p53
Studies related to p53 molecular mechanisms
Testing small molecules or biologics for cancer drug development
Type Strain
no
Biosafety Level
1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Comments
The Breast Cancer p53 Hotspot Mutation Cell Panel is comprised of 8 select cell lines derived from breast cancer that have been sequenced and validated by ATCC. The panel includes both WT p53 cell lines as well as cultures with p53 hotspot mutations at codons 175, 248, 249, or 273.
