| Comments |
Restriction digests of the clone give the following sizes (kb): EcoRI--19.5, 11.0, 3.9, 3.6, 3.1, 1.9, 1.8, 1.35, 0.9, 0.84; HindIII--20.0, 7.0, 6.2, 5.3, 4.7, 4.6, 1.85, 1.55, 1.0; BamHI--18.0, 14.0, 7.8, 6.0, 4.2, 3.2, 1.55; XbaI--18.0, 14.3, 8.2, 4.3, 3.7, 2.55, 1.7, 1.43; KpnI--19.0, 14.0, 8.5, 6.2, 3.6, 1.55. Enzyme(s) not detecting polymorphism: BglI, EcoRI, HindIII, HincII, MspI, PstI, RsaI (panel of 5 individuals). |
| References |
Schumm JW, et al. Identification of more than 500 RFLPs by screening random genomic clones. Am. J. Hum. Genet. 42: 143-159, 1988. PubMed: 2892396
Donis-Keller H, et al. A genetic linkage map of the huma genome. Cell 51: 319-337, 1987. PubMed: 3664638
Solomon SD, et al. A locus for familial hypertrophic cardiomyopathy is closely linked to the cardiac myosin heavy chain genes, CRI-L436 and CRI-L329 on chromosome 14 at q11-q12. Am. J. Hum. Genet. 47: 389-394, 1990. PubMed: 1975475
|
