| Comments |
Restriction digests of the clone give the following sizes (kb): PstI--2.5, 0.4; EcoRI--3.0; HindIII--3.0; EcoRI/HindIII--2.4, 0.5; SalI/EcoRI--3.0. The insert contains the complete coding sequence plus 5' (about 56 nucleotides) and 3' (about 110 nucleotides) of non-coding sequence. There is an APOC1 pseudogene 6 kb 3' to the functional C1 gene. The insert detects two mRNA species of 580 and 560 bases. |
| References |
Knott TJ, et al. Chromosomal localization of the human apoprotein CI gene and of a polymorphic apoprotein AII gene. Biochem. Biophys. Res. Commun. 125: 299-306, 1984. PubMed: 6095840
Knott TJ, et al. Characterisation of mRNAs encoding the precursor for human apolipoprotein CI. Nucleic Acids Res. 12: 3909-3915, 1984. PubMed: 6328444
Lusis AJ, et al. Regional mapping of human chromosome 19: organization of genes for plasma lipid transport (APOC1, -C2, and -E and LDLR) and the genes C3, PEPD, and GPI. Proc. Natl. Acad. Sci. USA 83: 3929-3933, 1986. PubMed: 3459164
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