Biological understanding of top genetic alterations in lymphoma
Novel anti-cancer drug targeting
Reactivation of mutant p53
Studies related to p53 molecular mechanisms
Testing small molecules or biologics for cancer drug development
Biosafety Level
2 [Cells contain herpes virus]
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Comments
The Lymphoma p53 Hotspot Mutation Cell Panel is comprised of five select suspension cell lines derived from lymphomas. Mutations have been sequenced and validated by ATCC. This panel includes a cell line with WT p53 as well as cell lines with p53 hotspot mutations at codons 248 and 273
