| Insert |
DNA: genomic Insert lengths(kb): 2.0 Gene product: immunoglobulin gamma 2 (Gm marker) [IGHG1] Alleles: A1, A2, A3, A4, A5, A6, , , , , C2, A1, B1, D2, A2, C1, B2, D1 |
| Comments |
Restriction digests of the clone give the following sizes (kb): EcoRI/HindIII--2.8, 2.05; EcoRI--4.9; HindIII--4.9. Contains the hinge, exon 2 and exon 3 of the IGHG3 gene. Subcloned from lambdaEZZgamma3. |
| References |
Huck S, et al. Sequence of a human immunoglobulin gamma 3 heavy chain constant region gene: comparison with the other human C gamma genes. Nucleic Acids Res. 14: 1779-1789, 1986. PubMed: 3081877
Ghanem N, et al. Definition of the RFLP alleles in the human immunoglobulin IGHG gene locus. Eur. J. Immunol. 18: 1059-1065, 1988. PubMed: 2900147
Ghanem N, et al. Restriction fragment haplotypes in the human immunoglobulin IGHG locus and their correlation with the Gm polymorphism. Eur. J. Immunol. 18: 1067-1072, 1988. PubMed: 2900148
Bensmana M, et al. The human immunoglobulin pseudo-gamma IGHGP gene shows no major structural defect. Nucleic Acids Res. 16: 3108, 1988. PubMed: 3130612
Huck S, et al. A gamma 3 hinge region probe: first specific human immunoglobulin subclass probe. FEBS Lett. 208: 221-230, 1986. PubMed: 2877902
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