| 產品名稱 |
Murine leukemia virus |
| 商品貨號 |
B162865 |
| Classification |
Retroviridae, Gammaretrovirus, Mammalian virus group |
| Agent |
Murine leukemia virus |
| Strain |
292A |
| Applications |
Does not produce plaques in XC assay. |
| Positive for Mycoplasma |
Yes |
| Biosafety Level |
2
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
| Isolation |
Pool of spinal cord extracts from naturally paralyzed wild mice, Lake Casitas |
| Product Format |
frozen |
| Storage Conditions |
-70°C or colder |
| Comments |
Typical type C retrovirus. Amphotropic. Not identical to dual-tropic agents isolated from pre-leukemic mice. Does not produce plaques in XC assay. This item has tested positive for mycoplasma by PCR but not by culture. |
| Effect on Host |
No, in vitro effects: Cytopathic effects in SC-1 cells Paralysis and lymphoma in mice; induces plaques ringed by clusters of dead cells in PG-4 (ATCC® CRL-2032™); no CPE in SC-1. Yes, in vitro effects: induces plaques ringed by clusters of dead cells in PG4 (feline S+L-) in tissue culture Yes, in vivo effects: paralysis and lymphoma in mice |
| Recommended Host |
Homo sapiens
human
Felis catus
cat
Recommended Host:? M. dunii? (ATCC® CRL-2017™) |
| Growth Conditions |
Duration: Variable; temperature 37C |
| Name of Depositor |
M Gardner |
| Source |
Pool of spinal cord extracts from naturally paralyzed wild mice, Lake Casitas |
| References |
Rasheed S, et al. Amphotropic host range of naturally occuring wild mouse leukemia viruses. J. Virol. 19: 13-18, 1976. PubMed: 181592
The preferred intact host is an Fv-1 n mouse.
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