波多野结衣毛片-乳色吐息在线观看-国产伦子伦对白视频-性做久久久-狠狠干2019-黄色裸体片-美女无遮挡免费网站-国产91熟女高潮一区二区-懂色av蜜臀av粉嫩av分享-小h片在线观看-台湾佬在线-日韩激情在线播放-欧日韩不卡在线视频-波多野结衣中文字幕一区-天天操夜夜草

熱門搜索:A549    293T 金黃色葡萄球菌 大腸桿菌 AKK菌
購物車 1 種商品 - 共0元
當(dāng)前位置: 首頁 > ATCC代理 > DC101
最近瀏覽歷史
聯(lián)系我們
  • 0574-87157013
  • mingzhoubio@163.com
  • 浙江省寧波市鎮(zhèn)海區(qū)莊市街道興莊路9號
  • 創(chuàng)e慧谷42號樓B幢401室
DC101
DC101
規(guī)格:
貨期:
編號:B164339
品牌:Mingzhoubio

標(biāo)準(zhǔn)菌株
定量菌液
DNA
RNA

規(guī)格:
凍干粉
斜面
甘油
平板


產(chǎn)品名稱 DC101
商品貨號 B164339
Organism Rattus norvegicus (B cell); Mus musculus (myeloma), rat (B cell); mouse (myeloma)
Tissue
Spleen
Cell Type hybridoma
Product Format frozen
Morphology lymphoblast
Culture Properties suspension
Biosafety Level 1

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.

Strain Lewis (B cell); BALB/c (myeloma)
Applications
DC101 was found to be specific for the murine tyrosine kinase receptor FLK-1. ELISA data showed that the antibody bound to purified FLK-1:SEAP but not alkaline phosphatase or other receptor tyrosine kinases such as FLK-2.
Treatment with DC101 antibody completely inhibits the growth of established epidermoid, glioblastoma, pancreatic, and renal human tumor xenografts by suppression of tumor-induced neovascularization
Storage Conditions liquid nitrogen vapor phase
Disclosure This material is cited in a US or other Patent and may not be used to infringe the claims. Depending on the wishes of the Depositor, ATCC may be required to inform the Patent Depositor of the party to which the material was furnished. This material may not have been produced or characterized by ATCC.
Derivation
Animals were hyperimmunized with an immune complex consisting of the mouse FLK-1:SEAPs soluble receptor, a rabbit anti-alkaline phosphatase polyclonal antibody and Protein-G sepharose beads.
Spleen cells were fused with NS-1 mouse myeloma cells.
Genes Expressed
immunoglobulin; monoclonal antibody; against murine vascular endothelial growth factor (VEGF) receptor-2 (Flk-1/KDR)
Cellular Products
immunoglobulin; monoclonal antibody; against murine vascular endothelial growth factor (VEGF) receptor-2 (Flk-1/KDR)
Comments
DC101 was found to be specific for the murine tyrosine kinase receptor FLK-1. ELISA data showed that the antibody bound to purified FLK-1:SEAP but not alkaline phosphatase or other receptor tyrosine kinases such as FLK-2.
DC101 does not cross-react with the human VEGFR2/KDR.
Treatment with DC101 antibody completely inhibits the growth of established epidermoid, glioblastoma, pancreatic, and renal human tumor xenografts by suppression of tumor-induced neovascularization
Complete Growth Medium The base medium for this cell line is ATCC-formulated Dulbecco's Modified Eagle's Medium, Catalog No. 30-2002. To make the complete growth medium, add the following components to the base medium: fetal bovine serum to a final concentration of 10%.
Subculturing
Protocol: Cultures can be maintained by the addition of fresh medium or replacement of medium. Alternatively, cultures can be established by centrifugation with subsequent resuspension at 2 X 10 exp5 viable cells/ml. Maintain cell density between 1 X 10 exp5 and 1 X 10 exp6 viable cells/ml.
Medium Renewal: Every 2 to 3 days
Cryopreservation
Freeze medium: Complete growth medium 92.5%; DMSO, 7.5%
Storage temperature: liquid nitrogen vapor phase
Culture Conditions
Temperature: 37.0°C
Isotype IgG1; kappa light chain
Name of Depositor ImClone Systems Inc.
Deposited As rat (B cell); mouse (myeloma)
U.S. Patent Number
References

Rockwell P, Goldstein NI. Monoclonal antibodies specific to VEGF receptors and uses thereof. US Patent 5,955,311 dated Sep 21 1999

Witte L, et al. Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy. Cancer Metastasis Rev. 17: 155-161, 1998. PubMed: 9770111

Prewett M, et al. Antivascular endothelial growth factor receptor (fetal liver kinase 1) monoclonal antibody inhibits tumor angiogenesis and growth of several mouse and human tumors. Cancer Res. 59: 5209-5218, 1999. PubMed: 10537299

Shaheen RM, et al. Effects of an antibody to vascular endothelial growth factor receptor-2 on survival, tumor vascularity, and apoptosis in a murine model of colon carcinomatosis. Int. J. Oncol. 18: 221-226, 2001. PubMed: 11172585

Kadambi A, et al. Vascular endothelial growth factor (VEGF)-C differentially affects tumor vascular function and leukocyte recruitment: role of VEGF-receptor 2 and host VEGF-A. Cancer Res. 61: 2404-2408, 2001. PubMed: 11289105

Kozin SV, et al. Vascular endothelial growth factor receptor-2-blocking antibody potentiates radiation-induced long-term control of human tumor xenografts. Cancer Res. 61: 39-44, 2001. PubMed: 11196192

Zimmermann RC, et al. Preovulatory treatment of mice with anti-VEGF receptor 2 antibody inhibits angiogenesis in corpora lutea. Microvasc. Res. 62: 15-25, 2001. PubMed: 11421657

Klement G, et al. Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity. J. Clin. Invest. 105: R15-R24, 2000. PubMed: 10772661

Stoelcker B, et al. VEGF/Flk-1 interaction, a requirement for malignant ascites recurrence. J. Inferon Cytokine Res. 20: 511-517, 2000. PubMed: 10841080

梅經(jīng)理 17280875617 1438578920
胡經(jīng)理 13345964880 2438244627
周經(jīng)理 17757487661 1296385441
于經(jīng)理 18067160830 2088210172
沈經(jīng)理 19548299266 2662369050
李經(jīng)理 13626845108 972239479
主站蜘蛛池模板: 相亲对象是问题学生动漫免费观看 | 欧美成人aaa片一区国产精品 | 欧美tv| 被各种性器调教到哭vk | 国产成人自拍一区 | 日韩啊啊啊 | 欧美美女性生活视频 | 国产精品免 | 成年人的毛片 | 欧美绿帽合集xxxxx | 日韩av免费一区 | 天堂99| 国产欧美精品一区二区 | 一本一道色欲综合网中文字幕 | 天天综合网网欲色 | 日韩高清一区 | 91精品视频网 | 天天干天天拍 | 成人网页在线观看 | 国产亚洲欧洲 | av福利在线| 国内精品嫩模av私拍在线观看 | 亚洲精品中字 | 瑟瑟视频免费看 | 在线理论视频 | 欧美18av| 日韩三级a | 国产精品久久久久久久久免费桃花 | 欧美色图片区 | 日韩一二三四五区 | 亚洲美女一区二区三区 | 五月婷婷影院 | 欧美老女人性视频 | 欧美老肥熟 | 91国内揄拍国内精品对白 | 人人插人人草 | 久久黄色一级片 | 日本视频在线播放 | 亚洲av综合色区无码二区爱av | 亚洲天堂日韩av | 亚洲一卡二卡在线 | 国产又粗又大又黄 | www一级片 | 欧美成人精品欧美一级 | 在线观看亚洲一区二区 | 成人午夜影视在线观看 | 毛片导航 | 亚洲毛片在线观看 | 91美女视频在线观看 | 娇妻被老王脔到高潮失禁视频 | 国产妇女馒头高清泬20p多 | 国产性xxx | 国产激情二区 | 中文在线a天堂 | 手机在线一区二区 | 成人免费黄色小视频 | 精品一区二区三区在线观看视频 | 欧美成人免费网站 | 香蕉视频免费看 | 成人美女视频 | 超碰天天操 | 麻豆传媒一区二区 | 免费午夜av | 日韩欧美亚洲 | 日本在线观看中文字幕 | 俄罗斯av在线 | av撸撸在线| 一本大道av | 国产成人在线视频观看 | 夜夜嗷| 亚洲欧美一区二区三区情侣bbw | 日本五十路在线 | 日本xxxx高清 | 国产精品久久久爽爽爽麻豆色哟哟 | 国产精品一区二区三区不卡 | 狠狠ri | 朝桐光av在线一区二区三区 | 69福利区| 在线观看日本一区二区 | 伊人av一区| 一本一道人人妻人人妻αv 国产一区二区在线视频观看 | 一个色的综合 | 草草影院第一页yycc.com | 久久免费看少妇高潮v片特黄 | 欧美色图1 | 免费国产| 国产精品无码无卡无需播放器 | 日本久操 | 精品一区在线视频 | 四虎精品欧美一区二区免费 | 亚洲三级在线看 | 日韩视频一区二区三区在线播放免费观看 | 成人性爱视频在线观看 | 污视频免费在线观看 | 1024久久| 亚洲精品传媒 | 在线成人欧美 | 亚洲激情网站 | 美女打屁股网站 |