transformation of: pergolide to pergolide sulfoxide and pergolide sulfone
Biosafety Level
1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Product Format
frozen
Storage Conditions
Frozen: -80°C or colder Freeze-Dried: 2°C to 8°C Live Culture: See Propagation Section
Type Strain
no
Preceptrol®
no
Medium
ATCC® Medium 336: Potato dextrose agar (PDA)
ATCC® Medium 324: Malt extract agar
ATCC® Medium 334: Oatmeal agar
Growth Conditions
Temperature: 24°C to 26°C
Atmosphere: Typical aerobic
Name of Depositor
CBS
Chain of Custody
ATCC <<--CBS<<--H.W. Wollenweber 4658
Isolation
Epichloe zahlbruckeriana, South Africa
References
Holmlund CE, et al. Stereospecific oxidation of a methylthio steroid to the sulfoxide by Calonectria decora. J. Org. Chem. 27: 1468-1470, 1962.
Clark AM, Hufford CD. Microbial transformations of the sesquiterpene lactone costunolide. J. Chem. Soc. Perkin Trans. 1979: 3022-3028, 1979.
Smith RV, et al. Microbial transformations of pergolide to pergolide sulfoxide and pergolide sulfone. J. Pharm. Sci. 72: 733-736, 1983. PubMed: 6684155
